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Is Sildenafil approved or not for the treatment of primary dysmenorrhea?

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Primary dysmenorrhea (PD) is the leading cause of pelvic pain in women, affecting both mental well-being and daily life. In the U.S. alone, it leads to 600 million lost work hours and costs around $2 billion each year (Dawood, 1984).

The pain is mainly caused by excessive prostaglandin production in the uterus during menstruation. This triggers strong contractions, increased uterine pressure, reduced blood flow, and heightened pain sensitivity. As the uterus contracts, blood flow to the endometrium decreases, suggesting that a lack of oxygen due to overactive muscles worsens the pain, making periods more uncomfortable for many women.

There are many options for the management of primary dysmenorrhea, but researchers are looking for new options like sildenafil. Let's explore what the study says so far for Sildenafil in the treatment of pain in primary dysmenorrhea.

The study by R Dmitrovic and team:

What They Did: Researchers wanted to see if sildenafil citrate (commonly used for circulation-related conditions) could help relieve menstrual pain when used as a vaginal treatment. Since menstrual cramps are often caused by poor blood flow and muscle contractions, they tested whether sildenafil could improve circulation and relax the muscles to reduce pain.

How They Did It: They conducted a study with 62 women, aged 18–35, who suffered from moderate to severe menstrual pain. These women were randomly given either a vaginal sildenafil citrate dose (100 mg) or a placebo. They then measured their pain levels over four hours using two different pain assessment methods.

What They Found: Women who received sildenafil citrate reported significantly less pain compared to those who got the placebo. The medicine improved blood flow to the uterus, which likely helped reduce pain. The results showed that sildenafil provided better relief at each time point and lowered pain scores considerably.

What Was the Conclusion? The study suggests that vaginal sildenafil citrate could be a promising treatment for menstrual cramps with no significant side effects. However, due to limited funding, the study was small, and more research is needed to confirm these findings before it can become a widely recommended treatment.

Hence, for now, sildenafil citrate is not approved for the treatment of pain in primary dysmenorrhea. But it is approved for the treatment of erectile dysfunction.

Sildenafil for erectile dysfunction!

Sildenafil citrate, the active ingredient in Kamagra Expo sildenafil 100mg, treats erectile dysfunction in men by improving blood flow to the targeted male reproductive organ. It helps to initiate and maintain an erection during stimulation. Please take it as prescribed by a healthcare provider. Possible side effects include stuffy nose, indigestion, flushing, and headache. Avoid alcohol and grapefruit juice when taking the pill.

What to Look for When Buying Wholesale Products as a Pharmacist or Small Business

If you’re a pharmacist or a small business owner looking to buy original products in bulk, it’s essential to choose wisely. Ensuring quality, authenticity, and reliability can protect your reputation and keep your customers happy. Here are the key factors to consider:

  1. Authenticity & Certification – Always source products from authorized distributors or manufacturers. Look for certifications, lab reports, and compliance with regulatory standards to guarantee quality.

  2. Trusted Suppliers – Work with well-established wholesalers who have a track record of providing genuine products. Read reviews, ask for references, and verify their sourcing practices.

  3. Proper Labeling & Packaging – Ensure that the products come in secure, tamper-proof packaging with clear labeling, including batch numbers, expiry dates, and ingredient lists.

  4. Regulatory Compliance – Check if the products meet local and international health and safety standards. This helps avoid legal issues and ensures your customers receive safe products.

  5. Competitive Pricing – While affordability is crucial, don’t compromise on quality. Extremely low prices can indicate counterfeit or substandard products.

  6. Customer Support & Return Policy – A good supplier offers reliable customer service and a fair return policy in case of defects or discrepancies.

  7. Avoid Counterfeits – Counterfeit products not only damage your business but can also pose health risks to consumers. Always double-check sources and verify authenticity before purchasing.

By considering these factors, you can confidently source high-quality, generic Kamagra EXPO 100mg products for your business while building trust with your customers.

Sildenafil shows promise for relieving menstrual pain, but more research is needed. For now, it's only approved for intimate-related issues. Always source authentic products from trusted suppliers to ensure quality and safety.

Disclaimer: This blog/content is for informational purposes only and should not be considered medical advice. Always consult a healthcare professional before starting any treatment. The content is not intended to diagnose, treat, cure, or prevent any condition. Purchase medications only from reputable sources to ensure safety and authenticity.

21.04.2025 11:04


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